Quimioterapia: acesso aberto
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Abstrato

EPR-Effect and Nano-medicine Backdoor or Bottleneck?

Gerhard Pütz

Cancers are a leading cause of death today as they will be in the future. Chemotherapy is one of the major weapons we have in the ill equipped battle against this important human threat. Despite several drawbacks, nanoparticle based drug delivery systems (DDS) hold promise to ameliorate anticancer chemotherapy. From the beginning of “Nano medicine” by the discovery of liposomes by Bangham et al. in 1965