Biologia Sintética e de Sistemas Atual
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Abstrato

Multivalent sugar-lectin interactions from glycoclusters on oligosaccharide scaffolds to self-assembling structures

Jose Kovensky

Sugars assume a fundamental part in a few natural capacities related
with specific associations with cell proteins that oversee a wide
assortment of life measures. In living beings, these high-fondness
carb protein cooperations happen through multivalent contacts,
described by an upgrade of the liking when the sugar ligand is introduced
in a bunch instead of alone. A few biomimetic approaches
have been created to get ready engineered multivalent neoglycoconjugates
to meddle with a progression of neurotic occasions, for
example, diseases due to infections and microbes, tumor movement
and relocation, and aggravation measures