Romil Stanislavov and Peter Rohdewald
Objective: Objective of the study was to evaluate the effect of PACR on sexual function and climacteric symptoms in peri-menopausal women. In addition, data of clinical chemistry and antioxidative capacity were collected.
Study design: In the double-blind, placebo-controlled study, 80 peri-menopausal women were supplemented with 4 tablets Lady Prelox® (PACR: Pine Bark Extract, L-Arginine, L-Citrulline, Rose Hip Extract) the day. Sexual function was evaluated by the Female Sexual Function Index (FSFI). Climacteric symptoms were ascertained by Women’s Health Questionnaire and questions from the Kupperman’s Index. Antioxidative activity and clinical chemistry was measured in blood samples of the participants by FSFI.
Results and conclusion: PACR improved sexual function as measured by 60% after 1 month and by 73% after 2 months treatment with PACR compared to baseline, increase of FSFI in the placebo group was only 40 and 46%. PACR relieved also climacteric symptoms evaluated by the Kupperman’s index and Women’s Health Questionnaire (WHQ). The efficacy of PACR was significantly superior compared to placebo. PACR also influenced metabolic parameters and antioxidant capacity of blood positively. No unwanted effects were reported. PACR improves sexual function and relieves climacteric symptoms in peri-menopausal women.