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Recent Advances in Cutaneous Lupus Erythematosus

Haya S. Raef , Jillian M. Richmond

Cutaneous Lupus Erythematosus (CLE) is an autoimmune disease that encompasses a wide range of dermatologic manifestations with varying degrees of association with systemic disease. Treatment options for CLE are limited, and no medication has been approved specifically for CLE. However, increased emphasis on the role of biological therapies for CLE has emerged in recent years due to an improved understanding of the pathogenesis of CLE. This review summarizes the recent insights into the pathogenesis of CLE and current advances in the development of CLE treatments.