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A Novel Immunoprofiling Technique for Diagnosing SLE AND Assessing Therapy Response

Chin Ko

SLE is a serious autoimmune illness that affects more women than males. Patients with SLE lose immunological tolerance to self-antigens (such as the high-mobility group protein 1) by an unknown mechanism, triggering autoreactive immune responses. Systemic inflammation (which includes lethargy, malar rash, and fever), immunological dysregulation (an elevated levels of autoantibodies as well as low serum complement contents), and damage to organs (such as nephritis, arthritis, and peripheral neuropathy) are common signs of SLE start. Notably, SLE diagnosis is difficult since early-onset SLE symptoms might be non-specific and mirror other more common illnesses.