Jornal de Toxicologia Clínica
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Acute Myopia Induced by Topiramate Plus Phentermine for the Treatment of Obesity

Jong-Su Park, Sung-Woo Lee, Su-Jin Kim and Yun-Sik Hong

Topiramate (TPM) iscurrently used for the treatment of epilepsy, migraine prophylaxis, bipolar diseases, and post-traumatic stress disorders. Recent studies reveal that a low-dose combination of Phentermine plus controlledrelease Topiramate (PHEN/TPM CR) as an adjunct to lifestyle modification reduces body weight in obese and overweight adults without significant side effects. We are reporting the case of an overweight young girl with acute progressive myopia due to topiramate, which was being used to treat her obesity.