Jornal de Doenças Infecciosas e Medicina Preventiva
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Asthma Exacerbation Caused by Bacterial Infection in Two Elderly Patients

Mutsuo Yamaya*, Hitomi Yoshigoe, Koji Murakami, Shoichi Nakayama and Masakazu Ichinose

Background: The role of airway bacterial infection in the asthma exacerbation has been reported in addition to that of viral infection. However, the effect of bacterial infections on asthma exacerbation has received less attention than that of viral infections, and clinical features have not been well reported.
Case presentation: Here, we describe the clinical features of two cases of asthma exacerbation that were thought to involve airway and/or lung bacterial infection and that improved with treatment including antibiotics, glucocorticoids and bronchodilators.
Conclusion: The examination data suggested that neutrophilic inflammation caused by bacterial infections may have an important role in the development of asthma exacerbations.