Avanços em Engenharia Genética
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Abstrato

Awareness and trends of Blood Cholesterol and Susceptibility to Develop Heart disease

Hari OS*1, Sonali G2, Sumitra N3

Objectives: Cholesterol is the essential steroids for life which created and used by our bodies to keep us healthy. Approximately 75% blood cholesterol produced from liver and ~25% produced from the food we eat. Hypercholesterolemia is a condition of abnormal cholesterol levels. Abnormal cholesterol levels are strongly associated with coronary heart disease. Therefore, we aimed to evaluate the awareness and frequency of trends of blood cholesterol levels (total cholesterol, LDL, HDL, triglycerides) and its associated complications.

Methods: This is a cross‐sectional pilot study. The total no. of participant consisted of 200. We enrolled 100 unrelated healthy individuals by door to door visit to check awareness status of blood cholesterol and 100 referral individuals of lab undergone for lipid profile were enrolled in this study. Blood cholesterol awareness was calculated using Microsoft excel version 7.0. Frequency of LDL, HDL and triglycerides were calculated using chi square by SPSS version 15.0 version.

Results: Frequency of awareness of blood cholesterol was found to be 29% among all survey participants while as frequency of awareness of blood cholesterol were found to be 54% and 4% among educated and non-educated participants. Frequency of Desirable Cholesterol Level was found to be higher (81.0%) as compared to Borderline High (19.0%) in between lab survey participants. Frequency of Above Optimal Low density lipoprotein (LDL) level was found to be higher (64.0%) as compared to above borderline high (27.0%) and high (9.0%) among lab survey participant. Frequency of Optimal High density lipoprotein (HDL) Level was found to be to be higher (94.0%) as compare to borderline low (5.0%) and high 1.0%) among lab survey participant. Frequency of Optimal Serum Triglyceride Level was found to be higher (53.0%) in optimal as compare to borderline high (33.0%) and High (4.0%) among lab survey participant.

Conclusion: The survey data of dore to dore visit strongly suggest the lack of awareness of blood cholesterol level and its associated complications among educated and non-educated people. Individuals with borderline high Serum triglyceride level may have the risk for heart disease and they may require for therapeutic intervention in Indian setting.