Jornal de Sinalização Celular
Acesso livre

Abstrato

Biological Target and Its Mechanism

He Zuan

Biological target is whatsoever within an alive organism to which some other entity (like an endogenous drug or ligand) is absorbed and binds, subsequent in a modification in its function or behaviour. For examples of mutual biological targets are nucleic acids and proteins. Definition is context dependent, and can refer to the biological target of a pharmacologically active drug multiple, the receptor target of a hormone like insulin, or some other target of an external stimulus. Biological targets are most commonly proteins such as ion channels, enzymes, and receptors. The term "biological target" is regularly used in research of pharmaceutical to describe the nastive protein in body whose activity is altered by a drug subsequent in a specific effect, which may a desirable therapeutic effect or an unwanted adverse effect. In this setting, the biological target is referred to as a drug target.