Anestesia e Pesquisa Clínica
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Comparison of Induction of Anesthesia Using High Concentration vs. Incremental Doses of Sevoflurane in Children

Shafi Imran, Alka Gupta, Namita Saraswat and Mohandeep Kaur

Background and aim: Three different strategies are used by anesthetists for inhalation induction with sevoflurane- Incremental Induction technique, High concentration primed-circuit technique, and Single Breath Vital Capacity technique. Although first two important techniques of induction have been used quite effectively and safely in children, yet most anesthetists prefer the incremental induction technique while ignoring the quick yet safe method of using high concentration sevoflurane. Considering this fact, we conducted this study to find out the best and safe method of induction among these two techniques.

Methods: A prospective, randomized study was conducted in Dr. RML Hospital .80 children of 2-12 years were randomly allotted into 2 groups of 40 each. Group A- High concentration primed-circuit; Group B- Incremental induction. The primary objective was to determine whether the induction time could be significantly shortened using sevoflurane with a high concentration primed-circuit method as compared to an incremental induction technique. Statistical testing was conducted with the statistical package for the social science system version SPSS 17.0.

Results: The time for induction of anesthesia could be significantly shortened using sevoflurane with a high concentration primed-circuit technique as compared to an incremental induction technique. The effect of both these techniques on hemodynamic and respiratory parameters is statistically insignificant and there is no significant difference in the change in the vital parameters with the use of high initial concentration of sevoflurane when compared to low initial concentrations.