Jornal de Ensaios Clínicos
Acesso livre

Abstrato

Complex Rehabilitation Project in Leigh Syndrome

Raoul Saggini, Scarcello L, Carmignano SM, Khodor H, Visciano C, Giuliani L and Bellomo RG

We describe the case of a 10 year old child with Leigh Syndrome. From 6 months of age, he developed eyelid, right upper limb clonus, sleep apneas, drooling, and hyperlactatemia, absence of the cough reflex, divergent strabismus, diffuse muscle wasting and dystonia. The MRI showed multiple lesions involving the lenticular nuclei, the thalami and cerebral peduncles and the periaqueductal front seat. The child has been undergoing since 2010, in the Department of Physical Medicine and Rehabilitation, “University ‘G. D’Annunzio” of Chieti, Italy, a specific rehabilitation project in order to maintain residual functionality, improve performance and tissue elasticity, stabilize metabolism and prevent the disease related complications.