Cloning  & Transgenesis

Cloning & Transgenesis
Acesso livre

ISSN: 2168-9849


D-Amino Acid Oxidase and Metagenomics

Gao Chen, Yulong Xie, Jie Deng, Yu Liu, Peihong Shen, Bo Wu, Chengjian Jiang

D-amino acid oxidase (DAAO, EC 1. 4. 3. 3) converts D-amino acid to a corresponding α-keto acid via deamination. D-amino acid oxidase is one of the most important enzymes responsible for maintenance proper level of D-amino acids, which play a key role in regulation of many processes in living cells. This paper summary the applications of D-amino acid oxidase in agricultural and industry practices, as the target in human disease treatments, etc. Most important of all, we demonstrate the importance of metagenomic library in exploring the novel D-amino acid oxidase from the environmental microbiology to optimize their applications.