Pediatria Clínica: Acesso Aberto
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EBV Positive Kawasaki Disease with False Positive SARS Antibodies in the Age of COVID-19 Pandemic

Hanna S Sahhar, Basch R.E, Downes. K

Kawasaki Disease (KD) is an inflammatory vacuities present primarily in pediatric patients; it is the leading cause of acquired heart disease in children of developed countries. The cause of KD is unknown but is presumed to be of infectious etiology. In this case, we report a 2-year-old female patient with a clinical diagnosis of KD who also has high levels of Epstein–Barr Virus (EBV) IgG and IgM antibodies. Many reported cases of KD have overlapping clinical symptoms with EBV. Interestingly, this patient also has false positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgM antibodies in the era of the COVID-19 pandemic. In this case report, we seek to discuss the significance of positive EBV antibodies and false positive SARS-CoV-2 IgM antibodies in the era of COVID-19 in a pediatric patient with a concomitant diagnosis of KD. We document this case to contribute to further understanding the relationship between EBV and KD with EBV as a possible trigger in a pediatric patient who also meets clinical criteria for Multisystem Inflammatory Syndrome in Children (MIS-C) during the COVID-19 pandemic.