Jornal de Pesquisa de Tumores
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Focus on Candidate Genes in Molecular Genetics Analyses for Breast Cancer Treatment

Ebubekir Dirican

Although a remarkable rise in the depth of our understanding and management of breast cancer (BCa) in the last decade, this matter is still a major public health problem the entire world. But, researchers investigate about reason of BCa. Especially, they detected some important genes (BRCA1/2, PIK3CA, MED12, CDH1, TP53, PTEN or SALL4) for BCa diagnosis or treatment. For this reason we reviewed about roles, functions or effects of these crucial genes in BCa. To determine candidate genes important in BCa processes need to be further analysis with a greater number of patients.