Jornal de Nanomedicina e Descoberta Bioterapêutica
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Green synthesis of silver nanoparticle using Clerodendrum paniculatum leaf extract

Parakkottil Chothi Madhu

Green synthesis of nanoparticles aims to diminish generated waste and implement sustainable processes. The green approach of nanoparticles synthesis possesses reduced or no toxicity. A number of plants and herbal extracts have been reported to be involved in such synthesis. Plant extracts contain number of secondary metabolites which has a vital role during the nanoparticle synthesis by acting as reducing or capping agents. Studies have shown that silver nanoparticles (AgNO₃) are highly stable and toxic to bacteria, fungus, and viruses. Therefore plant leaf extracts are considered to be an excellent and beginning source for metal as well as metal oxide nanoparticle synthetic process to facilitate nanoparticle synthesis. Similarly, plant leaf extract play a dual role by acting as both reducing and stabilizing agents in nanoparticle synthesis. It is extensively used in nanosystems and employed in various biomedical purposes. Various unorganized parts of the plants have been utilized for the synthesis of silver nanoparticles. Hence, the present study green synthesis of AgNO₃ was to synthesize nanoparticles by using aqueous leaf extract of the weed. It acts as a reducing agent and capping agent which synthesize and stabilizes the nanoparticle. Optimizations of parameters for maximizing the synthesis of silver nanoparticle were also carried out by plant extract concentration, incubation time and metal ion concentration. The synthesized nanoparticles were characterized by UV visible spectroscopy and it showed a peak at 440 nm and the maximum concentrations were obtained at 80mg/L.