Jornal de Oftalmologia Clínica e Experimental

Jornal de Oftalmologia Clínica e Experimental
Acesso livre

ISSN: 2155-9570

Abstrato

HIV Associated Eye Diseases: Existing Cognitive and Possible Mechanisms

Tie Zhao

The Human Immunodeficiency Virus-1 (HIV-1) envelope protein gp120 is the major contributor to the pathogenesis of retinopathy and uveitis in HIV-1-related eye diseases. Disruption of the structure and function of the Blood-Retina Barrier (BRB) is the major contributor of HIV-1-related eye diseases and the molecular mechanism remains unknown. Our mini review revealed that retinopathy and uveitis are required for gp120- induced inflammation and epigenetic changes and suggest that gp120 regulate tight junction protein.

Isenção de responsabilidade: Este resumo foi traduzido com recurso a ferramentas de inteligência artificial e ainda não foi revisto ou verificado.
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