Jornal Internacional de Medicina Física e Reabilitação
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Hypocalcemia and Acute Traumatic Coagulation Disease

Yajun Zou1, Hu Li2, Long Teng1, Qiangqiang Wang1, Xingyu Wang1, Jianlin Zhang1*

Although trauma surgeons have generally improved the treatment of various types of trauma worldwide, trauma remains the second leading cause of human death, accounting for approximately 40% of pre-hospital deaths and 10% of global deaths. Deaths caused by post-traumatic bleeding account for approximately 40% of the total number of traumatic deaths. Trauma has a high mortality rate because it often combines with a serious complication, namely, Acute Traumatic Coagulation (ATC). The pathogenesis of ATC is diverse, and post-traumatic hypocalcemia is often a neglected cause. Therefore, this article primarily reviews the causes of post-traumatic hypocalcemia and the mechanism by which post-traumatic hypocalcemia leads to ATC.