Jornal de Pesquisa em Dermatologia Clínica e Experimental
Acesso livre
ISSN: 2155-9554
ISSN: 2155-9554
Cheryl Lee Eberting
Irritant contact dermatitis is an extremely common condition resulting from epidermal exposure to any number of skin irritants. Upon contact with skin irritants, the epidermis develops many identifiable problems including specific epidermal lipid deficiencies, elevated epidermal pH with concomitant suppression of epidermal lipid production, pHdependent susceptibility to infection, inflammation, and aberrant calcium gradients. By addressing these problems simultaneously, and through irritant avoidance, the treatment of irritant contact dermatitis can be maximized.