ISSN: 2161-0401
Gashaw Nigussie
Rumex nervosus belongs to the family of Polygonaceae, which is traditionally used in Ethiopia to treat various diseases.
This prompted us to isolate bioactive compounds from the root of this plant. Ground root parts of Rumex nervosus
were subjected to exhaustive extraction successively with petroleum ether and methanol. The solvent from each
extract was evaporated under reduced pressure using rotavapour to obtain petroleum ether and methanol extract.
Chromatographic purification of the methanol extracts by Column chromatography followed by Preparative Thin
layer Chromatography using Chloroform: methanol (9.5:0.5) ratio gave a compound coded as RN-6. The structure of
this compound 4-ethylheptyl benzoate was characterized as by means of 1H NMR, 13C NMR, UV and IR spectral
data.