Jornal de Metabolismo e Toxicologia de Drogas
Acesso livre

Abstrato

Microbial Transformations of Plant Origin Compounds as a Step in Preparation of Highly Valuable Pharmaceuticals

Blaga Mutafova, Sava Mutafov, Pedro Fernandes and Strahil Berkov

The aim of the paper is to present microbial transformation reactions as a step in the preparation of drugs or their key intermediates from plant derived compounds. Described are some successful applications of microbial transformation processes for preparation of steroid drugs and/or their important intermediates as well as some microbial transformations of terpenes, alkaloids, flavonoids and poly(phenols) affording derivatives with improved biological activities.