Doenças Micobacterianas
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Molecular diagnosis of Mycobacterium Tuberculosis: A review

Augustine Chijioke Udefi and Victor Olaosebikan

There is an ongoing demand to shorten the turnaround time for accurate detection and monitoring of tuberculosis infection, which is an advantage the molecular methods possess over conventional methods. The objective was to review various molecular diagnostic methods and how it can be applied for the detection of this pathogen. A broad and thorough search through peer reviewed publications, conferences, articles, and a book was the method adopted for this review. It was found that molecular techniques aided the detection of antimicrobial resistance in addition to sensitive and specific detection of the pathogen, which leads to reduction in morbidity and mortality due to lesser complications attributed to delayed turnaround time.