Jornal de Oftalmologia Clínica e Experimental
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Myelinated Retinal Nerve Fibers inna Children: OCT Imaging, Refractive Error an Vision

Scott O'Brien, Derek T Sprunger, Maria E Lim an Jingyun Wang

Purpose: Fi characterize peripapillary retinal nerve fiber layers (RNFL's) an macular retinal structure inna children wid unilateral myelinated retinal nerve fibers (MRNFs). Wi also investigate di correlation between MRNF abnormalities an refractive error/visual acuity.
Methods: Twelve children (7-13 years old) wid MRNFs did include. Fourier domain optical coherence tomography did use fi image both di peripapillary RNFL an di macular retinal structures inna 6 patients. Using di instrument's segmentation software, global RNFL thickness an central subfield thickness (CST) a di macula did analyze. Planimetry did use fi quantify di MRNF area weh dem did observe pan fundus photography. Visual acuity an cycloplegic refractive errors (spherical equivalent) dem did record tu. Results fram di MRNF-affected eye did compare wid di fellow eye.
Results: Di global RNFL thickness a di eyes wid MRNFs (152 ± 13.9 μm) was significantly higher dan di fellow eyes (114.3 ± 15.2 μm) (P=0.003). Di global RNFL thickness a di fellow eye did inna normal range, an no significant differences did detect inna macular CST between di eyes wid MRNFs an fellow eyes (P=0.403). Di MRNF area was significantly correlated wid di spherical equivalent a di affected eye (P=0.002). In addition, di interocular difference a RNFL thickness between eyes was significantly correlated wid anisometropia (P=0.03).
Conclusions: Eyes wid MRNFs show a significantly thicker global peripapillary RNFL trend as compared to di fellow eye, an di area a MRNFs is correlated wid di development a myopia an anisometropia, but not correlated to visual acuity.