ISSN: 2168-958X
Yamuna Varanasi
Among Ca2+ -dependent (C-type) creature lectins, the chicken hepatic lectin (CHL) is special in showing nearly total selectivityfor N-acetylglucosamine over other monosaccharide ligands. The gem structures of the carbohydrate-recognition space (CRD) from serum mannose-binding protein (MBP) and of a complex between the CRD from liver MBP and the methyl glycoside of Nacetylglucosamine were utilized to show the official location in CHL. Substitution of parcels of CHL into the MBP system did not considerably increment selectivity.