Quimioterapia: acesso aberto
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Prognosis of Pancreatic Cancer in Hamadan, Iran (2008-2018)

Nazari Saman1, Elham Khanlarzadeh2, Mehdi Ghobakhlou3, Hossein Ranjbar3, Sasan Nazari1*

Purpose: The present study aimed to determine the prognosis of pancreatic cancer from 2008 to 2018 in Hamadan, Iran.

Methods: A case series study was conducted retrospectively at Beheshti Hospital in Hamadan, Iran. A total of 409 cases that had been diagnosed with pancreatic cancer from 2008 to 2018 were assessed. The variables included age, gender, pathological type, location involved, early symptoms, metastasis, prognosis and treatments, was extracted from the files and recorded in checklist. Data were analyzed by using SPSS/20 software.

Results: The mean of age was 66.23 ± 13.06 year. The most frequent of pancreatic cancers was Adenocarcinomas (66.7%). The highest frequency of early symptoms was jaundice (53.1%) and weight loss (12.7%). The highest frequency of pancreatic cancer lesions was more in the head of pancreas (68.7%). Most patients had metastasis at the beginning of diagnosis (82.3%). Most metastases were in liver (31.5%) and peritoneum (25.2%). The prognosis of the pancreatic cancer is significantly related to the lesion location and the consumption of alcohol, cigarettes and substance abuse (p<0.05), but it wasn’t correlated with age, sex and pathological type (p>0.05). The 1-year and 5-year survival rates were (22.3%) and (9.5%), respectively. The lowest and the highest in 5-year survival rate were (7.8%) and (18.8%) in adenocarcinoma and carcinoma type. More preventive considerations were found to be beneficial among this population.