ISSN: 2471-9315
Qiu Ling Wang*, Qing-Jie Xue, Li Zhang
Based on the research of recombinant BCG (rBCG) vector vaccine for many years, we recombined BZLF1 and LMP2 gene into BCG vector and studied its immunological mechanism and function in vivo and in vitro, which laid a solid foundation for the application of recombinant BCG vector vaccine, in this paper, the reason of using BZLF1 and LMP2 gene and the function of BCG vector are summarized.