Design de Medicamentos: Acesso Aberto
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Reproducible Clinical Research

Shein-Chung Chow and Fuyu Song

In clinical research, a non-reproducible research finding is not considered a valid science. Non-reproducible research findings could be biased and hence misleading in clinical research and development. It is then strongly suggested that in addition to the validity and reliability of the research findings, the probability of reproducibility be assessed based on the observed research findings. In this short commentary, a Bayesian approach for evaluation of reproducibility probability of the observed research findings is proposed.