Jornal de Oftalmologia Clínica e Experimental
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Retinal Angiomatous Proliferation in Adult Onset Coat's Disease Angiomatous Proliferation in Coat's Disease

Nurgül Örnek, Tevfik Oğurel , Kemal Örnek, Hatice Ayhan Güler

A 31 year old female patient had decreased vision in her left eye for several months. Visual acuity was 20/20 in right eye and counting fingers from 2 m in left eye. Examination of left eye demonstrated massive macular exudation with grayish discoloration of central macula and, aneurysmal and telangiectatic vessels with surrounding exudation in temporal mid peripheral retina. Optical coherence tomography of left eye showed findings consistent with neovascular complex, pigment epithelial detachment, subretinal fluid and involvment of choroid. There was hyperfluorescent focus with perfusing retinal arteriole and draining venule at the fovea which was compatible with retinal angiomatous proliferation (RAP) in early phase fundus fluorescein angiography and leakage was observed in late phase. After 3 doses of monthly-injected intravitreal ranibizumab and argon laser photocoagulation applied on aneurysmal and telangiectatic vessels, we observed central macular fibrosis, minimal lipid exudation and no macular edema. So retinal angiomatous proliferation may be a feature of adult onset Coats’ disease.