Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
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Severe Spontaneous Ovarian Hyperstimulation Syndrome With Cervical insufficiency: A Case Report

Emine Demirel, Ugur Turhan, Emre Ekmekci, Aslı Subasioglu and Sefa Kelekci

Objective: Spontaneous OHSS (sOHSS) is an extremely rare condition in natural conceived pregnancy, it’s most often seen in cases of multiple or molar gestations, hypothyroidism and polycystic ovary syndrome. Severe form is a rare entity in singleton pregnancy with spontaneous ovulation and may cause laparotomy because of misdiagnosis such as ovarian tumors or severe complications. We report a rare case of spontaneous severe OHSS.

Case report: We report a rare case of spontaneous severe OHSS accompanied by cervical insufficiency at second trimester in singleton pregnancy. The patient was applied at 11th weeks of gestation with abdominal pain, dyspnea, ascites that was diagnosed OHSS. We managed expectantly without complications.

Conclusion: Although spontaneous OHSS a rare condition, it’s important to consider OHSS in cases of bilateral enlarged cystic ovaries in pregnancy. Early diagnosis and successful management is essential to avoid serious complications, which may develop rapidly and may lead significant morbidity and mortality.