Espectrometria de Massa e Técnicas de Purificação
Acesso livre

Abstrato

Tumor spheroids in three-dimensional biopolymer networks

Ilia Brondz

Three-dimensional traction force microscopy for single cells in a nonlinear lattice is computationally perplexing because of the variable cell shape, here we misuse the circular evenness of tumor spheroids to determine a scaleinvariant connection between spheroid contractility and the encompassing network disfigurements. This relationship permits us to straightforwardly decipher the size of lattice misshapenings to the absolute contractility of subjectively measured spheroids. We show that our strategy is exact up to strains of half and stays legitimate in any event, for unpredictably molded tissue tests while thinking about just the distortions in the far field.