Pediatria e Terapêutica
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Abstrato

Understanding Dynamics: Probing into Gut Health and Dietary Interventions on Biomarkers of Inflammation in Rheumatoid Arthritis

Akanksha Srivastava

It Rheumatoid arthritis (RA) is a debilitating and disabling autoimmune disorder characterized by joint pain, stiffness and lost muscle function. About 1% of population accounts for individuals suffering from this disease and 30% of RA patients find it difficult to perform daily task in a span of next 10 years of the onset of the condition. Moreover, it is observed that women are more affected than men between the ages of 40-70 years; children are also affected at any age. It causes painful inflammation and subsequent cartilage and bone destruction owing to pro inflammatory triggers like IL-6, cytokines, TNF-α with no clear signs in the starting. Current drug treatment for treating rheumatoid arthritis is expensive and deleterious on overall health on long-term use. Gut abnormalities can be an underlying cause of disease activity in RA. RA in a pre-disposed condition starts in the gut and may run in the families.