Pediatria Clínica: Acesso Aberto
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Wilms Tumor: An Example Of Risk-Adapted and Well Tolerated Therapy

Khyati D Shah and Peter M Anderson

Wilms tumor (WT) is the most common malignant renal tumor in children. It can present with an abdominal mass and macroscopic hematuria. A 2 year old boy presented with acute onset of bilious vomiting and macroscopic hematuria. He was diagnosed with Stage 4 WT with lung metastasis and treated with risk-adapted therapy. Initial surgery was followed by risk based chemotherapy; lung radiation was needed and he currently remains in remission. Due to the recent advances in treatment based on risk stratification of WT, the overall survival for children diagnosed with WT has increased, but treatment of lung metastases can be challenging.