Jornal de Pesquisa e Desenvolvimento

Jornal de Pesquisa e Desenvolvimento
Acesso livre

ISSN: 2311-3278

Abstrato

Antifungal Activity of Loaded Chitosan Nanoparticles With S-nitrosomercaptosuccinic acid against Candida sp.

Gabriela Jesús Morón Atencio

Introduction: Candida sp species are fungal pathogens that affect patients with risk pathologies. Due to the change in their conventional drug susceptibility patterns, it is necessary to investigate therapeutic alternatives. It is proposed to evaluate the antifungal potential of nitric oxide (NO), by administering it in the donor s-nitrosomercaptosuccinic acid (MSA-NO), encapsulated in chitosan nanoparticles (Np) to improve its bioavailability and inhibit the growth of Candida albicans, glabrata, krusei and parapsilosis.

Isenção de responsabilidade: Este resumo foi traduzido com recurso a ferramentas de inteligência artificial e ainda não foi revisto ou verificado.
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