Virologia e Micologia
Acesso livre

Abstrato

Antiviral Activity of a Marine Seaweed Tubinaria Ornata (Turner) J. Agardh (Phaeophyceae) Against Herpes Simplex Virus Ii (HSV-II)

Poonam Sethi

Turbinaria ornata marine brown seaweed found along the coastal areas of Rameswaram, Tamil Nadu, and India was screened in vitro for antiviral activity against Herpes Simplex Virus-2.Two extracts one aqueous and the other ethanolic (95%) were screened for activity. The extracts were subjected to Pretreatment assay (whereby the plant extract is added before the addition of virus to the cell line) and post treatment assay (whereby the plant extract is added after the addition of virus to the cell line). Abundance of this algae on the shores during the month of November in the coastal waters of Rameswaram was intuited to select this alga, in addition to this the solvent extracts were non cytotoxic to the cell line. On the other hand dextran sulphate was used a positive control and the bioactive compounds efficacy was compared with it.