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Body Weight and Hematological Parameter Change in the Advanced Breast Cancer Following Adjuvant Chemotherapy

Mohamad Luthfi, Indra Wijaya

 Body weight change commonly occurs in breast cancer patients who receive adjuvant chemotherapy. However, there was lack of information associated with weight loss and hematological parameter change. The purpose of this study was to evaluate the body weight and hematological parameter change following adjuvant chemotherapy in advanced breast cancer. This prospective observational study included 50 advanced breast cancer (Stage IIIB and stage IV) subject who were receiving adjuvant chemotherapy with Doxorubicin and Cyclophosphamide regiment. Body weight, Body Mass Index (BMI), Body Surface Area (BSA) and hematological parameter were measured before the onset of chemotherapy, then after first and second cycles of chemotherapy.