Jornal de Toxicologia Clínica
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Calcium Channel Blocker Induced Thrombocytopenia in the Intensive Care Unit: A Rare Presentation and Review of the Literature

Allen L Zhou*, Markus Gutsche

Thrombocytopenia, defined as a platelet count of less than 150,000 platelets/uL in an adult, can have many causes including medications, infections, nutritional deficiencies, as well as autoimmune disorders. Commonly, drug- induced thrombocytopenia has been reported with heparin, sulphonamides, carbamazepine, and gold for rheumatoid arthritis, haloperidol, ibuprofen, naproxen, phenytoin, platinum chemotherapeutics, and quinidine. We present the case of a 58-year-old female with severe thrombocytopenia attributed to a Calcium Channel Blocker (CCB) overdose, a very rare cause of thrombocytopenia.