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Cu/Fe-Catalyzed Carbon-Carbon and Carbon-Heteroatom Cross-Coupling Reactions

Niranjan Panda, Ashis K. Jena

Copper and iron salts are less toxic and  inexpensive as compared to other transition metal salts. These salts have been extensively used for various carbon-carbon and carbon-heteroatom cross-coupling reactions. In this review, we described the Cu and Fe-mediated C-C, C-N, C-O, C-S and C-Se coupling reactions extensively. The synergistic effects of copper and iron salts towards the various bond-forming reactions have been presented. Use of such methods in the synthesis of bioactive molecules were also highlighted.