Endocrinologia e Síndrome Metabólica

Endocrinologia e Síndrome Metabólica
Acesso livre

ISSN: 2161-1017

Abstrato

Effect of the Endoplasmic Reticulum Stress on Diabetes Mellitus Type 2 in Hypothalamic Cells

Mesquita C, Ferreira D and Assaly V

Unfolded protein response is an adaptive cellular response that adjust protein translation rate to specific external stress. This response has been demonstrated to mediate programmed cell death and insulin resistance in pathophysiological conditions such as diabetes. More recently, it has been demonstrated that the pharmacological activation of UPR in the hypothalamus is able to stimulate food intake through mechanism not completely determined.

Isenção de responsabilidade: Este resumo foi traduzido com recurso a ferramentas de inteligência artificial e ainda não foi revisto ou verificado.
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