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Enantioselective Michael Addition of Diethyl Malonate on Substituted Chalcone Catalysed by Nickel-Sparteine Complex

Manojkumar U Chopade

A series of transition metal with Sparteine a novel chiral catalyst was facilely synthesized, all of which contain a chiral Sparteine unit as a bidentate ligand. These bidentate chiral auxiliaries were found to be an efficient chiral catalyst in nickel-mediated, enantioselective Michael addition of Diethyl malonate to substituted chalcone. The corresponding adducts were obtained in good yields (80-91%) under simple and clean reaction condition.