Jornal de Oftalmologia Clínica e Experimental
Acesso livre

Abstrato

Epidemio-Clinical Profile a di Symbpharon during Toxic Epidermal Necrolysis (TEN) at di Institute of African Tropical Ophthalmology-Teaching Hospital

Elien GYRR, Bakayoko Seydou, Dicko Mahamat Adam, Thera JP

Introduction: Symblepharon a one lesion pan di ocular surface weh associate or not wid ocular adnexa damage. Symblepharon is characterized by di formation a one adhesion between di palpebral conjunctiva an di bulbary conjunctiva. Deh have plenty causes a symblepharon, mongst which toxic epidermal necrolysis a di most well-known an documented due to di extreme severity a ocular damage. So di purpose a dis study is fi describe di epidemiological-clinical profile a di symbpharon during di toxic epidermal necrosis fi adequate an appropriate management.
Methodology: Dis was a cross-sectional study, lasting 24 months fram 18 March 2018 to 17 March 2020 at CHUIOTA. All patients weh did consent an did have di symblepharon regardless a sex an age did compile inna a nonprobability sample.
Results: Durin di 2 years, 11 patients did get collect. Dem did have 4 Man an 7 Woman. Di average age a wi patients dem was 36.81 14.60 years, di age extremes did range fram 7 years old to 65 years old. Di association a Nevirapine an Cotrimoxazole did frequently incriminate inna 36.4% a wi patients. More dan half a di symblepharon dem did deh anterior (55% a di cases).
Discussion: Di bilaterality a ocular damage woulda be related pan di one han tu di immunological mechanisms a toxic epidermal necrolysis, an di association a Nevirapine wid Cotrimoxazole pan di ada han.
Conclusion: A rare disease, toxic epidermal necrolysis often lead to severe ocular complications.