Jornal de Sinalização Celular

Jornal de Sinalização Celular
Acesso livre

ISSN: 2576-1471

Abstrato

Functional Roles of Protein Arginine Methyltransferase 5 in Cardiovascular Diseases

Fang Yang, Wei Shu and Ming Chen*

Protein arginine methyltransferase 5 (PRMT5) is a protein arginine methyl transferase that catalyzes the symmetrical dimethylation of arginine residues within target proteins. PRMT5 is shown to associate with and methylate histone or non-histone proteins in cells, and plays key roles in cell development, survival and apoptosis. In this review, the current state of knowledge and functional roles of PRMT5 in vascular systems are discussed.

Isenção de responsabilidade: Este resumo foi traduzido com recurso a ferramentas de inteligência artificial e ainda não foi revisto ou verificado.
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