Plantas medicinais e aromáticas
Acesso livre
ISSN: 2167-0412
ISSN: 2167-0412
Abdelgadir A Abdelgadir*, Hozeifa M Hassan, Abeer M Eltaher, Khnsaa GA Mohammed, Lamya AA Mohammed, Tassneem B Hago, Tassneem H Aboalbashar, Tbyan H Aalim, Alia M Ahmed, Alaa K Mohamed
Hyperlipidemia is the greatest risk factors that precipitate coronary heart disease. Medicinal may confer hypolipidemic effects in order to compliment the cardiovascular diseases treatment regimen. The aim of this study was to investigate hypolipidemic effect of cinnamon bark ethanolic extract in Triton X-100 induced hyperlipidemic in rats. Twenty five adult male albino rats (150-250 g) were randomly divided into five groups: group A stand as negative control, group B stand as positive control, groups C and D received 250 and 500 mg/kg cinnamon extract respectively and group E received atorvastatin 10 mg/kg after of induction of hyperlipidemia by Triton X-100 for seven days. The results was showed a significant (p<0.05) hypolipidemic effect on cholesterol and triglycerides of cinnamon extract in groups administered 250 and 500 mg/kg compared with the negative and positive control group. Also the hepatic histopathological study was showed that the cinnamon ethanol extract has preventive effect from liver fatty infiltration and granular degeneration.