Anestesia e Pesquisa Clínica
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Perioperative Management of Patient with Factor XI Deficiency Undergoing Total Knee Arthroplasty

Eric Kamenetsky and Sherif Afifi

Factor XI (FXI) deficiency is a rare, inherited bleeding disorder that is typically asymptomatic and presents with unexpected bleeding after surgery or trauma. We present a patient with FXI deficiency that underwent total knee arthroplasty (TKA) under general anesthesia and received peripheral nerve blocks for postoperative analgesia. We also present a review of literature focused on presentation of FXI deficiency in various surgical settings and choices of perioperative anesthetic management.