Biologia Sintética e de Sistemas Atual
Acesso livre

Abstrato

Roles of PARP-1 and PALB2 in controlling deoxyribonucleic acid resection and strand invasion during DSB repair

Jean Masson

Endogenous DNA twofold strand breaks (DSBs) are incredibly
perilous for a cell. Whenever left unrepaired, DSBs can drive
cells to genomic precariousness and tumor improvement. Our
research facility centers around the unpredictable organization of
homologous recombination (HR) catalysts liable for fixing DSBs.