Pediatria Clínica: Acesso Aberto
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The Complexities, Recent Advancements of Neonatal Encephalopathy and its Significant Complications to Healthcare Providers

George Mary, Robert Houston

Neonatal encephalopathy is a serious condition that affects newborn infants, often leading to long-term neurological complications if not addressed promptly. This condition presents significant challenges for both parents and healthcare providers, requiring a comprehensive understanding of its causes, symptoms and treatment options. Affected infants experience an initial hypoxic/ischemic event with cell death and subsequent downstream sequelae including excitotoxicity, oxidative damage and inflammation. Numerous biomarkers have been investigated in infants to assist physicians with predicting outcomes and evaluating treatments in infants with neonatal encephalopathy. In this study, we will discuss into the complexities of neonatal encephalopathy and its complexities and exploring the latest advancements in its management.