Jornal de Doenças Infecciosas e Medicina Preventiva
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The COVID-19 Infection Impact on the Values of Thyroid Hormones

Dumitru Cristinel Badiu, Gabriel Cristian Popescu, Anca Zgura, Adriana Mercan Stanciu, Mihai Daniel Dodot, Letitia Toma, Razvan Simu, Bogdan Haineala, Nicolae Bacalbasa, Dragos Serban

The COVID-19 pandemic has proven an important test in the ability of the scientific medical world to effectively understand, describe and manage pathophysiology processes when dealing with aggressions from newly emerged pathogens. As time progresses, more and more studies are published reflecting the systemic impact of what was originally thought to be a respiratory infection. It appears that COVID-19 can directly affect the cardiovascular system, the gastrointestinal system (including the liver and the pancreas), the renal system, and the nervous and musculoskeletal systems. Furthermore, due to the abundance of ACE2 and TMPRSS2 receptors in the thyroid, required for the internalization of the virus, it seems likely that SARS-CoV-2 may affect the thyroid directly, as well as in the context of an increased systemic inflammatory response.