Jornal de Depressão e Ansiedade
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The Role of Supplements in Treatment of Depression

Seyed Mostafa Mansouripour and Dharmendra Kumar

Along with dietary intake, nutrition can also be obtained from nutrient supplements. They are widely used in the general population and their market is growing. It has been assumed adequate intake of them contributes to better overall mental health. This review explores studies regarding the role of different nutrients in treatment of depression. After searching among them we found Testosterone, Omega 3 fatty acid, Thyroid hormones, Modafinil, Folate, Vitamin B12, S-Adenosyl Methionine (SAMe), Magnesium, and Zinc as supplements which has some effect in combination with anti-depressant medications. They have advantages and also some disadvantages. In this review paper, we have taken a look at each of these agents individually and mentioned their current status in the treatment of depression.