Anatomia e Fisiologia: Pesquisa Atual
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Analysis of Chromosomal Aberrations in PBL of Chrome Tanning Industrial Workers

Anusha C Pawar, S Jithender Kumar Naik, M V Raghavendern Rao, K Sireesha V Mangesh and S Anitha Kumari

In order to monitor the geno-toxic effects of chromium compound, 160 chrome tanning industrial workers (80 each of smoker and non-smoker) were selected from a leather tanning industry to perform the cytogenetic protocol of chromosomal aberrations in the peripheral blood lymphocytes. The workers were further classified into two groups on the basis of their personnel habit (Smoker and Non-Smokers) and on the duration of their employment (1-5, 6-10 and 11-15 years). Even 120 individuals (62 smokers and 58 non-smokers) were also selected as controls for the purpose of comparison. A statistically significant increased frequency of total chromosomal aberrations was observed in the chrome tannery workers (6.20 ± 0.12) as against the control (1.61 ± 0.09). The increased frequencies of aberrations were duration dependent. Even higher incidence of chromosome aberrations was reported among the smoker group of both control and exposed workers. The results clearly establish the mutagenic nature of the chromium compound in human beings.