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Anti-Influenza Activity of Monoterpene-Containing Substituted Coumarins Using Physicochemical Parameters

Suresh Kumar and Rekha Kumari

A Quantative-Structure-Activity Relationship (QSAR) study is performed on monoterpene-containing substituted coumarins, A number of highly descriptive and predictive QSAR models for these compounds were obtained by Using physicochemical parameters using stepwise-multiple linear regressions methods. Model validation is performed by incorporating training and test sets approach and calculating R2 which is equal to 0.9943 and also Regression analysis data has indicated that activity can be best modeled in multi-parametric regression.