Quimioterapia: acesso aberto
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Biomarkers to Therapy, do they Exist in Hepatocellular Carcinoma?

Jennifer Wu

Hepatocellular carcinoma (HCC) is the 3rd leading cause of cancer
death worldwide and its incidence in the world, including USA, has
persistently climbed over the last 4 decades, largely due to the obesity
epidemic and increasing incidence of patients with hepatitis C.
Alpha fetal protein (AFP) has traditionally been the serum biomarker
to increase the suspicion of HCC in patients with risk factors with
both sensitivity and specificity below 75%, although its utility in
predicting effect of chemotherapy in HCC is less well defined