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Effects of Lifestyle Modification on Pregnancy Success in Obese and Overweight Women with PCOS

Artemis Karkanaki, Ioannis Kalogiannidis and Dimitrios Panidis

The present review approaches the pregnancy success after lifestyle modification in obese infertile women
with Polycystic Ovary Syndrome (PCOS). Lifestyle modification including hypocaloric diet, structured exercise and counseling, in combination with medical intervention, where necessary, is effective on the resumption of menstruation, the amelioration of the reproductive profile and the success of spontaneous pregnancy. Pregnancy rates vary a lot among the studies. There are limitations due to the heterogeneity in the design of the studies, the diagnosis of the syndrome and the type of the intervention. The number of the studies is restricted and raises the need for further evaluation through well designed, controlled trials. Despite the controversies, the evidence supports the lifestyle modification as first line therapy in obese and overweight women with PCOS.